What is Vitamin C Serum?
Vitamin C is one of the most important vitamins the body needs, especially for the skin, due to its countless benefits. It is considered one of the best antioxidants for the skin.

But when we talk about Vitamin C, we must first understand free radicals (Free Radicals).
đż What are Free Radicals?
Free radicals are single, unstable electrons that are considered the primary cause of skin problems. They lead to skin discoloration, pigmentation, and premature aging signs by damaging skin cells and reducing collagen production in the skin.
This is why we need antioxidantsâthey work by neutralizing free radicals, donating an electron to stabilize them, and preventing them from causing harm to the skin
Effects of Free Radicals on the Skin:-
Formation of dark spots and uneven skin tone.
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Dull, tired-looking skin.
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Increase in the appearance of dark circles under the eyes.
The Importance of Vitamin C as an Antioxidant for the Skin
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Evens out skin tone
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Reduces the appearance of acne scars and marks
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Stimulates collagen production, reducing signs of aging
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Enhances the effectiveness of sunscreen by providing extra protection from harmful UV rays
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Boosts skin hydration
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Gives the skin a radiant, glowing appearance
How to Choose a Vitamin C Serum
There are many Vitamin C products on the market, with different prices and formulations. Here are some key things to look for:
The Right Ingredients:
You wonât always find the words "Vitamin C Serum" on the label. Instead, look for products labeled with "Ascorbic Acid" or "L-Ascorbic Acid"âthis is Vitamin C specifically formulated for the skin.
Concentration 10% - 20%:
Choose a serum thatâs not too weak or too strong. Less than 10% ascorbic acid may not deliver the results you want, while more than 20% significantly increases the risk of skin irritation.
No Clear Bottles:
Vitamin C is sensitive to sunlight, heat, and light. Always choose a serum packaged in dark or tinted bottles to protect its potency.
How to Apply Vitamin C Serum
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Start with a patch test:
If you have sensitive skin, itâs recommended to begin by testing a small amount of the serum with a low concentration of Vitamin C on the inner forearm. Monitor the area for any signs of irritation. Based on the reaction, you can decide whether to discontinue or proceed with regular use. -
Apply to clean skin:
Use the serum on a freshly cleansed face. Gently apply and spread it evenly over your entire face. -
Follow with your moisturizer:
Moisturizing after Vitamin C serum is an essential step. It helps prevent oxidation of the serum when exposed to air, which in turn protects the skin from darkening or discoloration.
The Best Time to Apply Vitamin C Serum
Itâs recommended to apply Vitamin C serum in the early morning. Recent studies have confirmed that Vitamin C works synergistically with sunscreen to protect the skin from pollutants and harmful UV rays. However, Vitamin C serum can also be applied at night in your evening skincare routine to ensure better absorption and maximize its benefits. The key is to apply the serum daily at the same time to achieve optimal results.
Store your serum bottle away from sunlight, humidity, or bright lights, as Vitamin C is a compound that oxidizes quickly and is highly sensitive to light, which reduces its effectiveness.
How to Combine (or Not Combine) Other Active Ingredients with Vitamin C Serum
With so many skincare products to choose from, it can be confusing to know what to combine with Vitamin C (and what to avoid). Thatâs why weâre here to help you understand how to integrate Vitamin C and other ingredients into your skincare routine for the best results while protecting your skin.
 How to Combine Vitamin C with Other Ingredients:
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Hyaluronic Acid:
The easiest way to use Vitamin C and hyaluronic acid together is to buy a product that contains both. If youâre using them separately, apply the lighter-textured product first, followed by the thicker one. -
Moisturizer:
No matter what type of moisturizer you use, always apply Vitamin C serum first, then follow with your moisturizer. -
Sunscreen:
Always apply sunscreen as the last step in your morning routine. -
AHAs and BHAs (Alpha & Beta Hydroxy Acids):
Avoid layering these with Vitamin C in the same routine. Instead, use them at different times of day, or purchase a product formulated with both, specifically designed to work together at the correct pH level. -
Benzoyl Peroxide:
Benzoyl peroxide can oxidize Vitamin C, reducing its effectiveness. To avoid this, use them at different times of the day or on separate days. -
Niacinamide:
You can either use a product that combines both ingredients or apply them separately, layering the heavier or oil-based product last.
If youâre using niacinamide with Vitamin C, itâs better to choose a gentler form of Vitamin C like Sodium Ascorbyl Phosphate, Magnesium Ascorbyl Phosphate, or Tetrahexyldecyl Ascorbate, rather than pure ascorbic acid. -
Retinol:
Use Vitamin C serum and retinol at different times of the day (or on alternate days). This helps reduce irritation. In general, Vitamin C is ideal for daytime use, while retinol is better at night. Alternatively, choose a product that combines both in a formula with a pH level suitable for your skin. -
Ferulic Acid:
Helps boost the effectiveness of Vitamin C serum and creates a more even skin tone when combined with Vitamin C in the same product.
Medical Products and Serums Containing Vitamin C
For effective results with Vitamin C, it is recommended to use a complete skincare routine containing Vitamin C products (cleanser, toner, serum, moisturizer, micellar water). Consistent use for at least 6 weeks is essential to achieve the desired outcome.
Serums that Contain Vitamin C in Their Formula
LA ROCHE POSAY PURE VITAMIN C10 SERUM
If youâre looking for a Vitamin C serum that also includes multiple active ingredients, this serum from La Roche-Posay is a great option. Itâs marketed as an anti-aging product, but itâs also an excellent choice for anyone with acne-prone skin because it contains salicylic acid, which helps unclog pores and prevent future breakouts.
In terms of Vitamin C, the serum contains 10% ascorbic acid, a concentration thatâs effective without causing irritation. It also includes neurosensine, a soothing ingredient that helps calm sensitive skin. Additionally, it contains glycerin and hyaluronic acid, which provide extra hydration and help plump the skin.

A serum containing 10% pure and active Vitamin C, it fights free radicals and signs of aging. Itâs the ideal choice if youâre looking for a product that combines Vitamin C and hyaluronic acid for enhanced radiance and to fill in lines and wrinkles.
One of its standout features is its guaranteed freshness of active ingredients for 21 days after opening. All you have to do is press and shake the bottle to mix the Vitamin C powder into the serum upon first use.
This product is suitable for all skin types and begins to show visible results within 7 days of consistent use.

This serum contains a high concentration of 20% Vitamin C, making it highly effective in delivering the desired results. Itâs a powerful antioxidant that encourages the skinâs natural collagen production.
The formula also includes hyaluronic acid, which enhances skin radiance and plumps the skin. Moreover, it enables water-soluble active ingredients to penetrate deeply into the skin.
Itâs suitable for all skin types, and its effects start to become visible after 7 days of regular use.

Its effectiveness becomes visible within 6 days of use. It helps reduce dark spots and dark circles.

ISDIN ISDINCEUTICS FLAVO-C ULTRAGLICAN ANTIOXIDANT AMPOULES
This serum works to increase hydration and reduce signs of aging on the skin. It fights the damage caused by UV rays and is ideal for an anti-aging focused routine.
All these benefits are possible thanks to a formula that combines the antioxidant power of 5% Vitamin C, proteoglycans, and hydrating hyaluronic acid.
Itâs suitable for normal and dry skin.

FILORGA C RECOVER RADIANCE ANTI-FATIGUE CONCENTRATE 3 VIALSÂ
This serum is ideal for those who are heavily exposed to pollution and oxidative stress and want to prevent the appearance of premature aging signs.
It boosts skin radiance, restores vitality, and strengthens skin hydration thanks to the polysaccharide complex it contains.
The serum remains stable and fresh for 7 days after opening.


It contains a 10% concentration of Vitamin C in its formula, which helps stimulate collagen production, thereby reducing the appearance of signs of aging. It also treats dark spots on the skin.

It serves as a suitable base before makeup and primarily aims to reduce signs of aging and dullness. It contains pure ascorbic acid and is best used in the morning.

BALANCE VITAMIN C BRIGHTENING SERUM
It contains 6% ethyl ascorbic acid and 3% Stay-C, both of which are stable forms of Vitamin C. This serum brightens the skin and reduces dark spots. It has a lightweight texture and is suitable for all skin types.
Itâs considered one of the most effective serums for enhancing radiance and beauty of the skin, containing 20% Vitamin C and suitable for all skin types.
Daily use of this serum helps brighten and illuminate the skin, improving its texture day by day.

Examples of Cleansers that Contain Vitamin C in Their Formula
It is used to deeply cleanse the skin and is suitable for all skin types. It is recommended to use it twice daily for effective results.

Some Examples of Micellar Waters That Contain Vitamin C
Suitable for oily skin and contains 10% concentration of Vitamin C.

It removes makeup, adds radiance to the skin, and is suitable for all skin types.

There is also an example of makeup removers that contain Vitamin C.
It is used to remove waterproof makeup and is suitable for all skin types.

There are also types of Vitamin C in the form of sheet masks, such as:
This mask helps provide the skin with vitality and the hydration it needs.

As for creams that contain Vitamin C
It is the best-selling product due to its high effectiveness and fast results. It works to firm the skin, thereby reducing the appearance of signs of aging.
This cream is recommended for women who are seeking high-performance anti-aging care, overall skin health, and are interested in natural ingredients.

Myths About Vitamin C Serum
Myth #1: Pure Vitamin C Products Are Hard to Preserve and Lose Effectiveness Quickly
Itâs true that Vitamin C is unstable, making it a challenge for cosmetic labs. Thatâs why companies stabilize ascorbic acid (pure Vitamin C)âthe most effective formâat an optimal pH for the skin, making it more resistant to oxidation. They also package serums in opaque bottles to protect them from UV rays and light, ensuring they remain potent until the very last drop.
Myth #2: Pure Vitamin C Serum Irritates the Skin
Due to its potency, pure ascorbic acid has a reputation for irritating sensitive skin. To avoid this, serums are formulated at a skin-friendly pH and designed for better tolerance.
Myth #3: You Shouldnât Use Pure Vitamin C Serum in the Sun
On the contrary! Thanks to its powerful antioxidant properties, pure Vitamin C serum actually helps protect the skin from sun damage and delays photoaging, especially when combined with Vitamin E and UV filters. However, you still need to apply a broad-spectrum sunscreen for full protection.
Myth #4: Higher Concentrations of Pure Vitamin C Are Always More Effective
A higher concentration doesnât always mean better. If the Vitamin C isnât pure, stable, or bioavailable, it may be ineffective, cause irritation, or even promote oxidation. A concentration of around 20-30% is usually the most tolerable and effective for the skin.
Myth #5: Pure Vitamin C Serum is Only Beneficial for Mature Skin
By stimulating collagen and elastin production and fighting free radicals, pure Vitamin C serum enhances radiance and prevents early signs of aging. That means itâs also beneficial for younger skinâstarting in your twentiesâto achieve an immediate glow and long-term anti-aging benefits. Itâs never too early to start caring for your skinâs future.
Myth #6: You Can Get Enough Vitamin C for Your Skin Through Diet Alone
Studies show that only about one-third of the Vitamin C you consume from food reaches the skin. To ensure your skin has adequate protection against external stressors, dermatologists recommend applying Vitamin C topically as a serum for maximum absorption and effectiveness.
Myth #7: Pure Vitamin C Serum Doesnât Mix Well with Other Active Ingredients
Because pure Vitamin C is potent, itâs important to use it properly. As mentioned earlier in this guide, thereâs a right way to combine Vitamin C with other active ingredients safely and effectively.
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Who Should Avoid Using Vitamin C Products?
Vitamin C has been studied only in adults and is not recommended for children. Always read the ingredient list before purchasing a Vitamin C product. If you have a known allergy or sensitivity to any of the ingredients, donât hesitate to perform a patch test as mentioned earlier or consult your doctor before use.
If you have oily or acne-prone skin, consider using a formulation designed to control oil or one that contains ingredients like salicylic acid, which helps prevent breakouts.
And Finally: Eat Fruits and Vegetables
Itâs not just about cosmetics and serumsâVitamin C from food also helps promote healthy, glowing skin. Citrus fruits, tomatoes, peppers, kiwis, and strawberries are all rich sources of Vitamin C.